Stanley Yang and Kristen Onos from The Jackson Laboratory have contributed new scRNA-seq data on microglia in genetically diverse mouse models. Read the story and check out the data.

Dr. Gareth Howell and Dr. Kristen Onos

The Model Organism Development and Evaluation for Late-onset Alzheimer’s Disease (MODEL-AD) consortium discussed their goals, including the development of new models based on recent human genetics, the alignment of AD pathophysiology in mouse models and human studies, the staging of disease progression, and preclinical testing based on translatable biomarkers.

Dr. Gregory Carter is an Associate Professor at The Jackson Laboratory, Bar Harbor, ME. He combines genetic, genomic, imaging, and other data resources to understand the causes and progression of Alzheimer’s disease.