// From ‘Where to FAIR’
Curating and pre-processing the AddNeuroMed dataset
AddNeuroMed (ANM) was a public private partnership that established a longitudinal cohort from six different sites across Europe to develop and validate biomarkers in Alzheimer’s disease (AD). Colin Birkenbihl, a bioinformatician at Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), painstakingly curated this extensive dataset to fulfill the principles of FAIR (Findable, Accessible, Interoperable, and Reusable) science.
Dr. Hajjar is a neuroscientist and an Associate Professor of Medicine in the Departments of Neurology and Medicine (Geriatrics). His research is focused on the link between hypertension and vascular disease with brain health including cognitive performance, cerebrovascular function. In particular, he is studying the effects of antihypertensive medications that modulate the renin angiotensin system on both prevention of cognitive decline and as potential therapeutic modalities for early dementia.
Learn more about the NIA’s efforts to expand the use of open science through an array of new translational infrastructure programs. These programs – including AMP-AD and affiliated target discovery consortia (M2OVE-AD, Resilience-AD, and Psych-AD), and the MODEL-AD and TREAT-AD centers — operate under open science principles — to rapidly deliver data, knowledge, and research tools necessary to overcome key barriers to developing effective therapies for Alzheimer’s disease and related dementia. Read the full blog post from the Division of Neuroscience’s Suzana Petanceska and Lorenzo Refolo.
Congratulations to Anna Greenwood, Lara Mangravite, and team for the recent publication in Current Protocols in Human Genetics, providing protocols on how to use the Portal to discover and download genomic variant and transcriptomic data from the same individuals.
Read more on the three basic protocols detailed to help users leverage the multi -omics data available for their research: The AD Knowledge Portal: A Repository for Multi‐Omic Data on Alzheimer’s Disease and Aging.