Follow the Explore Data links to access files for each Model and Data Type.
Data for a specific model may be organized into multiple “Studies.” Each study has additional metadata. Follow the link in the Study column to view data files for this information.
Available Data
Models are deeply phenotyped with imaging, multi-omics, and behavioral modalities; some in varying environments and used in preclinical studies of candidate therapeutics. All data are shared via the AD Knowledge Portal. Below is current data from the MODEL-AD consortium including data from familial and late onset AD models.
Upcoming Data
Coming soon is data from new models and new data modalities including single cell RNA sequencing, microbiome sequencing, proteomics and metabolomics.
Model/Data Type | Gene Expression | sc-Gene Expression | Proteomics | Metabolomics | Microbiome Sequencing |
Trem2R47H | ⊕ | ||||
PicalmH465R | ⊕ | ||||
Bin1K358R | ⊕ | ||||
Abca7V1599M | ⊕ | ||||
3xTg-AD | ⊕ | ||||
5XFAD | ⊕ | ⊕ | ⊕ | ||
APOE4Trem2R47H | ⊕ | ⊕ | ⊕ | ||
C57BL6J | ⊕ | ⊕ |