Follow the Explore Data links to access files for each Model and Data Type.
Data for a specific model may be organized into multiple “Studies.” Each study has additional metadata. Follow the link in the Study column to view data files for this information.

  Available Data

Models are deeply phenotyped with imaging, multi-omics, and behavioral modalities; some in varying environments and used in preclinical studies of candidate therapeutics. All data are shared via the AD Knowledge Portal. Below is current data from the MODEL-AD consortium including data from familial and late onset AD models.

Model / Data Type Gene Expression Behaviour Electrophysiology Immunoassay Imaging Pharmakokinetics Blood Chemistry
5XFAD Explore Data Explore Data Explore Data Explore Data Explore Data Explore Data
5XFAD Levetiracetam treated Explore Data Explore Data Explore Data
APOE4KI Explore Data Explore Data Explore Data Explore Data Explore Data
APOE4Trem2R47H Explore Data Explore Data Explore Data Explore Data Explore Data
C57BL6J Explore Data Explore Data Explore Data Explore Data Explore Data
Trem2R47H Explore Data Explore Data Explore Data Explore Data Explore Data
APP.PS1 (mouse) Explore Data Explore Data
APP.PS1 (rat) Explore Data
hTauTrem2 Explore Data
ApoEKO Explore Data
B6.Clu Explore Data
B6.Gfap-APOE4 Explore Data
Bin1.B6 Explore Data
Cd2ap.B6 Explore Data
3xTg-AD Explore Data
hAbeta KI Explore Data
Abca7A1527GAPOE4Trem2R47H Explore Data Explore Data
Ceacam1KO Explore Data Explore Data
Clasp2L163PSNP Explore Data
hCR1KIAPOE4Trem2 Explore Data Explore Data
Il1rapKO Explore Data Explore Data
Kif21bT82TSNP Explore Data
Meox2KOHET Explore Data
MthfrC677TSNP Explore Data Explore Data
Mtmr4V297GSNP Explore Data
Snx1D465NSNP Explore Data

  Upcoming Data
Coming soon is data from new models and new data modalities including single cell RNA sequencing, microbiome sequencing, proteomics and metabolomics.

Model/Data Type Gene Expression sc-Gene Expression Proteomics Metabolomics Microbiome Sequencing
Trem2R47H
PicalmH465R
Bin1K358R
Abca7V1599M
3xTg-AD
5XFAD
APOE4Trem2R47H
C57BL6J