The 20.5.1 Data Release provides updates to the SEA-AD study.


  • The SEA-AD study

    This study provides transcriptomic and chromatin accessibility data from single nuclei isolated from brain tissue of 84 aged individuals spanning the full spectrum of Alzheimer’s disease severity and 5 neurotypical adult reference individuals. The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) consortium includes the Allen Institute for Brain Science, the University of Washington, and Kaiser Permanente Washington Health Research Institute. This release provides:

    • snRNAseq data for medial entorhinal cortex, primary visual cortex, superior temporal gyrus, and lateral entorhinal cortex tissue samples
    • snATACseq data for primary visual cortex tissue samples
    • 10x Multiome data for primary visual cortex tissue samples