The 18.10 Data Release includes a new computational tool and model for verubecestat.

Tools

  • MRGWAS

    Two Sample Mendelian Randomization was used to analyze the relationship between significantly associated Genome Wide Association Studies traits obtained from publicly available data containing 4,112 unique traits and four definitions of longevity. This web application allows for exploration of association results from all exposures and all four longevity outcomes.

Models

  • The Jax.IU.Pitt_Verubecestat_5XFAD study
    This study provides behavioral, immunoassay, and pharmacokinetic data on the 5xFAD familial Alzheimer’s disease mouse model dosed with verubecestat.