The MayoRNAseq Study
This study contains data from brain tissue from individuals with neuropathological diagnosis of Alzheimer’s disease, progressive supranuclear palsy, pathologic aging, or elderly controls without neurodegenerative diseases obtained from the Banner Sun Health Research Institute and the Mayo Clinic Brain Bank. Previously released from this study is RNAseq on bulk tissue from the temporal cortex and cerebellum, proteomics from the temporal cortex and GWAS and whole genome sequencing.
AD-BXD study: This study provides immunohistochemistry, behavioural data, and RNAseq on a genetically diverse mouse model. The RNAseq data was previously indexed from SRA. These links have been deprecated by NCBI. To access the RNAseq data go directly to GEO Series GSE101144.
This release adds an updated version of the tools section in the portal. Computational and Experimental tools are now under separate tabs. The Experimental tools include an updated set of Mouse Models created through the MODEL-AD program. Click on the title of the tool card for detailed information about the model through The Jackson Laboratory, and note links to studies where data has been generated on a model.