This study contains data generated from subjects participating in the Religious Orders Study (ROS) and Memory and Aging Project (MAP). These are longitudinal clinical-pathologic cohort studies of aging and AD run from Rush University. Previously released from these studies is GWAS, WGS, RNAseq on bulk and single nuclei from the dorsolateral prefrontal cortex, microglia RNAseq, array mRNA and miRNA expression, epigenetics, and metabolomics.
This release adds:
- Bulk RNAseq for ~1k dorsolateral prefrontal cortex and posterior cingulate cortex samples.
- Bulk RNAseq from monocytes for 615 blood samples.
- An update to the QC normalized TMT proteomic profiles searched against the UniProtKB human proteome database containing only Swiss-Prot canonical protein sequences downloaded Feb 11, 2019.