Alzforum: Mouse Model LOADs on the Alzheimer’s Risk Factors

A new article on Alzforum, Mouse Model LOADs on the Alzheimer’s Risk Factors, highlights research by Adrian Oblak and Gareth Howell demonstrating that LOAD2 mice show mild neurodegeneration and cognitive issues on a high-fat diet. Based on the recent pre-print in bioRxiv, Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer’s Disease Independent of Amyloid and Tau Pathology, the article describes how LOAD2 mice fed a fatty diet may offer a valuable model of preclinical AD