The AD Knowledge Portal and MODEL-AD will present the following posters at AAIC 2026 in London.
Throughout the week, our teams will be available to discuss these projects and answer questions. You can also connect with us in the NIH Pavilion at booth 901, and learn more about resources available at this year’s NIA-AA Symposium.
Multi-omics Profiling of Aducanumab-Induced Changes in Brain, CSF, and Plasma of 5xFAD Mice Highlights Mechanistic Benefits and Risks
Pandey et al.
The Rare Gga3 Ins545T Variant Drives Age-Dependent Alzheimer’s Disease-Relevant Pathway Dysfunction in Humanized Mouse Models
Spruce et al.
Utility of the APPSAA Knock-In Mouse Model for Preclinical Testing
Sloan et al.
Synaptic Integrity and Network Function Changes in LOAD2 Mice
Rangel-Barajas et al.
Age- and Diet-Dependent Brain Remodeling in a PLCγ2 M28L Late-Onset Alzheimer’s Disease Mouse Model
Rangel-Barajas et al.
Multimodal Characterization of MAPT-GR Mice in Model-AD Reveals Tauopathy-Linked Signatures Across Age and Genetic Contexts
Oblak et al.
Gene-by-Diet Effects in a Novel Humanized Late-Onset Alzheimer’s Disease Mouse Model Expressing APOE4, Amyloid-Beta, and Tau
Kotredes et al.
Integrated Phenotypic and Proteomic Screening Identifies Top-Tier Alzheimer’s Disease Therapeutic Targets
Cary et al.
Convergent Proteomic Signatures Across Human Neuronal Models of Alzheimer’s Disease
Cary et al.
Complete Functional Rescue of LTP Deficits Following Late-Stage Excision of Humanized Aβ
Gomez-Arboledas et al.
APOE4 Alters Glial Response to Amyloid-Beta Plaques in a Novel Mouse Model of Alzheimer’s Disease
Kwang et al.
Development of New Mouse Models of Alzheimer’s Disease That Combine Humanized Aβ, Tau, and APOE4 Knock-In Alleles
Barahona et al.
Temporal Excision of Human APP in a Novel Endogenous Knock-In Mouse Model (MODEL-AD2): Potential for Reversing AD Pathology
Butler et al.
Oligodendrocyte Remodeling Across Human Alzheimer’s Disease and Humanized Mouse Models of AD
Swarup et al.
Development of Next-Generation Mouse Models for Late-Onset Alzheimer’s Disease by the UCI MODEL-AD Consortium
Genaro et al.
Breeding Increases Pathology in a Humanized Mouse Model of Late-Onset Alzheimer’s Disease
Milinkeviciute et al.
Effects of APOE4 and TREM2 R47H Mutations on the Gut Microbiome in the hABKI Alzheimer’s Mouse Model
Mulay et al.
The Emory–Sage–SGC–JAX TREAT-AD Center: Systematic Target Prioritization and Tool Generation for Emerging Alzheimer’s Disease Targets
Karina Leal
Alzheimer’s Disease-Associated Module 42 Modulates Immune Function Independent of Amyloid-β In Vitro
Katerina Gospodinova
Demographic- and Cohort-Aware Comparison of Alzheimer’s Omic Risk Signatures
Joshua Manickam
Discovery of SFRP1–ADAM10 PPI and Peptides Targeting for Therapeutic Development in Alzheimer’s Disease
Elizabeth Zoeller
Genetic Determinants of Gene Expression Across Multi-Ethnic Populations and Their Role in Alzheimer’s Disease
Reddy et al.
Dysregulation of Circular RNAs in the Alzheimer’s Disease Brain Across Multi-Ethnic Populations
Cruz et al.